Download e-book for kindle: Antitumor Steroids by R T Blickenstaff

By R T Blickenstaff

Antitumor Steroids examines using steroids, in addition to nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the therapy of melanoma. It explains the mechanism during which steroids and their receptors interact to impact their physiological services commonly and their antitumor task particularly. It additionally describes the systematic screening of antitumor compounds remoted from usual resources.
Organized into 9 chapters, this booklet starts with an outline of the function of steroids in melanoma therapy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the subsequent chapters contemplate androgens, a few antiandrogens, derivatives in response to C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl workforce. The booklet explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor houses of clearly happening corticosteroids; sterols and cucurbitacins; diet D and its metabolites; and cardenolides, bufadienolides, and withanolides. The publication concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This e-book is a invaluable source for natural and medicinal chemists biochemists, and pharmacologists drawn to using steroids in treating cancer.

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Antitumor Steroids by R T Blickenstaff

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